000 02435nam a22003017a 4500
001 saulb0009139
003 BD-SyAU
005 20170704174013.0
008 170704s2014 enk b 001 0 eng
020 _a9781107030787 (hardback)
020 _a9781107690943 (paperback)
040 _aDLC
_beng
_cDLC
_erda
_dDLC
_d170704
082 0 0 _a590.724
_223
_bBAD
100 1 _aBate, Simon T.,
_d1975-
_94734
245 1 4 _aThe design and statistical analysis of animal experiments /
_cSimon T. Bate, GlaxoSmithKline, UK, and Robin A. Clark, Huntingdon Life Sciences, UK.
260 _aCambridge, United Kingdom :
_bCambridge University Press,
_c2014.
300 _axv, 310 pages ;
_c26 cm.
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
504 _aIncludes bibliographical references (pages 297-302) and index.
505 8 _aMachine generated contents note: Preface; Acknowledgements; 1. Introduction; 2. Statistical concepts; 3. Experimental design; 4. Randomisation; 5. Statistical analysis; 6. Analysis using InVivoStat; 7. Conclusion; Glossary; References; Index.
520 _a"Written for animal researchers, this book provides a comprehensive guide to the design and statistical analysis of animal experiments. It has long been recognised that the proper implementation of these techniques helps reduce the number of animals needed. By using real-life examples to make them more accessible, this book explains the statistical tools employed by practitioners. A wide range of design types are considered, including block, factorial, nested, cross-over, dose-escalation and repeated measures and techniques are introduced to analyse the experimental data generated. Each analysis technique is described in non-mathematical terms, helping readers without a statistical background to understand key techniques such as t-tests, ANOVA, repeated measures, analysis of covariance, multiple comparison tests, non-parametric and survival analysis. This is also the first text to describe technical aspects of InVivoStat, a powerful open-source software package developed by the authors to enable animal researchers to analyse their data and obtain informative results"--
_cProvided by publisher.
650 0 _aAnimal experimentation
_xStatistical methods.
_94735
650 0 _aExperimental design.
_94736
700 1 _aClark, Robin A.,
_dsoftware developer.
_94737
942 _2ddc
_cBK
999 _c3239
_d3239